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1

Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges

Sneddon, Julie B., Tang, Qizhi, Stock, Peter, Bluestone, Jeffrey A., Roy, Shuvo, Desai, Tejal, Hebrok, Matthias

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2018

2

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

Wen, Li, Ley, Ruth E., Volchkov, Pavel Yu., Stranges, Peter B., Avanesyan, Lia, Stonebraker, Austin C., Hu, Changyun, Wong, F. Susan, Szot, Gregory L., Bluestone, Jeffrey A.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 354 KB

english, 2008

3

T reg cells—the next frontier of cell therapy

Bluestone, Jeffrey A., Tang, Qizhi

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2018

4

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways

Brian T. Fife, Jeffrey A. Bluestone

Journal:

Immunological Reviews

Année:

2008

Langue:

english

Fichier:

PDF, 321 KB

english, 2008

5

Genetics, pathogenesis and clinical interventions in type 1 diabetes

Bluestone, Jeffrey A., Herold, Kevan, Eisenbarth, George

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 7.38 MB

english, 2010

6

Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials

Esensten, Jonathan H., Bluestone, Jeffrey A., Lim, Wendell A.

Journal:

Annual Review of Pathology Mechanisms of Disease

Année:

2017

Langue:

english

Fichier:

PDF, 935 KB

english, 2017

7

NextGen cell-based immunotherapies in cancer and other immune disorders

Azimi, Camillia S., Tang, Qizhi, Roybal, Kole T, Bluestone, Jeffrey A

Journal:

Current Opinion in Immunology

Année:

2019

Langue:

english

Fichier:

PDF, 732 KB

english, 2019

8

Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation

Christiane Ferran, Kathleen Sheehan, Michel Dy, Robert Schreiber, Sylvie Merite, Paul Landais, Laure-Hélène Noel, Georges Grau, Jeffrey Bluestone, Jean-François Bach, Lucienne Chatenoud

Journal:

European Journal of Immunology

Année:

1990

Langue:

english

Fichier:

PDF, 1.93 MB

english, 1990

9

Suppressor T cells – they’re back and critical for regulation of autoimmunity!

Lucienne Chatenoud, Benoît Salomon, Jeffrey A. Bluestone

Journal:

Immunological Reviews

Année:

2001

Langue:

english

Fichier:

PDF, 223 KB

english, 2001

10

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

Todd M. Brusko, Amy L. Putnam, Jeffrey A. Bluestone

Journal:

Immunological Reviews

Année:

2008

Langue:

english

Fichier:

PDF, 420 KB

english, 2008

11

Opinion-Regulatory Lymphocytes: Natural versus adaptive regulatory T cells

Bluestone, Jeffrey A., Abbas, Abul K.

Journal:

Nature Reviews Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2003

12

In Vitro Characterization of Five Humanized OKT3 Effector Function Variant Antibodies

Danlin Xu, Maria-Luisa Alegre, Sally S. Varga, Annette L. Rothermel, Alexander M. Collins, Virginia L. Pulito, Lewis S. Hanna, Kevin P. Dolan, Paul W.H.I. Parren, Jeffrey A. Bluestone, Linda K. Jollif

Journal:

Cellular Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 145 KB

english, 2000

13

Plasticity of Human Regulatory T Cells - Characterization of IFN-γ-Producing Cells

Stephanie McClymont, Amy Putnam, Michael Lee, Jonathan Esensten, Weihong Liu, Sven Olek, Udo Baron, Ulrich Hoffmuller, Jeffrey Bluestone, Todd Brusko

Journal:

Clinical Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 56 KB

english, 2010

14

CD28/B7 SYSTEM OF T CELL COSTIMULATION

Lenschow, Deborah J., Walunas, Theresa L., Bluestone, Jeffrey A.

Journal:

Annual Review of Immunology

Année:

1996

Langue:

english

Fichier:

PDF, 193 KB

english, 1996

15

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

Elizabeth A. Tivol, Frank Borriello, A.Nicola Schweitzer, William P. Lynch, Jeffrey A. Bluestone, Arlene H. Sharpe

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 9.81 MB

english, 1995

16

Notch 1 Signaling Regulates Peripheral T Cell Activation

Todd N Eagar, Qizhi Tang, Michael Wolfe, Yiping He, Warren S Pear, Jeffrey A Bluestone

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 373 KB

english, 2004

17

Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease

DuPage, Michel, Bluestone, Jeffrey A.

Journal:

Nature Reviews Immunology

Année:

2016

Langue:

english

Fichier:

PDF, 665 KB

english, 2016

18

Is autoimmunity the Achilles' heel of cancer immunotherapy?

June, Carl H, Warshauer, Jeremy T, Bluestone, Jeffrey A

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 868 KB

english, 2017

19

Chance favours the prepared mind

Bluestone, Jeffrey A.

Journal:

Nature Reviews Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 321 KB

english, 2018

20

Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again

Bucktrout, Samantha L., Bluestone, Jeffrey A., Ramsdell, Fred

Journal:

Genome Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 765 KB

english, 2018

21

New Frontiers in the Treatment of Type 1 Diabetes

Warshauer, Jeremy T., Bluestone, Jeffrey A., Anderson, Mark S.

Journal:

Cell Metabolism

Année:

2019

Fichier:

PDF, 2.41 MB

2019

22

The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance

Todd N. Eagar, Nitin J. Karandikar, Jeffrey A. Bluestone, Stephen D. Miller

Journal:

European Journal of Immunology

Année:

2002

Langue:

english

Fichier:

PDF, 157 KB

english, 2002

23

The immune tolerance network and rheumatic disease: Immune tolerance comes to the clinic

Betty Diamond, Jeffrey Bluestone, David Wofsy

Journal:

Arthritis & Rheumatism

Année:

2001

Langue:

english

Fichier:

PDF, 149 KB

english, 2001

24

The presence of a common idiotype in anti-H-2 immune sera as detected by anti-idiotype to a monoclonal anti-H-2 antibody

Keiko Ozato, Suzanne L. Epstein, Jeffrey A. Bluestone, Susan O. Sharrow, Ted Hansen, David H. Sachs

Journal:

European Journal of Immunology

Année:

1983

Langue:

english

Fichier:

PDF, 649 KB

english, 1983

25

Anti-idiotypes against anti-H−2 antibodies VI. Detection of shared idiotypes among monoclonal anti-H−2 antibodies

Jeffrey A. Bluestone, Hugh Auchincloss Jr., David H. Sachs, Matthias Fibi, Günter J. Hämmerling

Journal:

European Journal of Immunology

Année:

1983

Langue:

english

Fichier:

PDF, 710 KB

english, 1983

26

Cross-reactive recognition by antigen-specific, major histocompatibility complex-restricted T cells of a mitogen derived from Mycoplasma arthritidis is clonally expressed and I-E restricted

David H. Lynch, Barry C. Cole, Jeffrey A. Bluestone, Richard J. Hodes

Journal:

European Journal of Immunology

Année:

1986

Langue:

english

Fichier:

PDF, 557 KB

english, 1986

27

Cytotoxic T lymphocyte recognition of a xenogeneic major histocompatibility complex antigen expressed in transgenic mice

Jeffrey A. Bluestone, Mark D. Pescovitz, William I. Frels, Dinah S. Singer, Richard J. Hodes

Journal:

European Journal of Immunology

Année:

1987

Langue:

english

Fichier:

PDF, 720 KB

english, 1987

28

Cascade modulation by anti-tumor necrosis factor monoclonal antibody of interferon-γ, interleukin 3 and interleukin 6 release after triggering of the CD33/T cell receptor activation pathway

Christiane Ferran, Michel Dy, Kathleen Sheehan, Robert Schreiber, Georges Grau, Jeffrey Bluestone, Jean-Francois Bach, Lucienne Chatenoud

Journal:

European Journal of Immunology

Année:

1991

Langue:

english

Fichier:

PDF, 513 KB

english, 1991

29

Evidence for programmed cell death of self-reactive γδ T cell receptor-positive thymocytes

Alexander L. Dent, Louis A. Matis, Jeffrey A. Bluestone, Stephen M. Hedrick

Journal:

European Journal of Immunology

Année:

1993

Langue:

english

Fichier:

PDF, 1004 KB

english, 1993

30

Distinct roles of CTLA-4 and TGF-β in CD4+CD25+ regulatory T cell function

Qizhi Tang, Elisa K. Boden, Kammi J. Henriksen, Helene Bour-Jordan, Mingying Bi, Jeffrey A. Bluestone

Journal:

European Journal of Immunology

Année:

2004

Langue:

english

Fichier:

PDF, 218 KB

english, 2004

31

Expression of CTLA-4 and FOXP3 in cis protects from lethal lymphoproliferative disease

Shunsuke Chikuma, Jeffrey A. Bluestone

Journal:

European Journal of Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 186 KB

english, 2007

32

Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation

Todd Brusko, Jeffrey Bluestone

Journal:

European Journal of Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 147 KB

english, 2008

33

Cell-surface molecules involved in T-cell functions

Jeffrey A Bluestone, Richard J Hodes

Journal:

Immunology Today

Année:

1983

Langue:

english

Fichier:

PDF, 461 KB

english, 1983

34

The regulation of the immune system

Richard J Hodes, Ronald N Germain, Jeffrey A Bluestone

Journal:

Immunology Today

Année:

1984

Langue:

english

Fichier:

PDF, 844 KB

english, 1984

35

The B7 and CD28 receptor families

Carl H. June, Jeffrey A. Bluestone, Lee M. Nadler, Craig B. Thompson

Journal:

Immunology Today

Année:

1994

Langue:

english

Fichier:

PDF, 1.37 MB

english, 1994

36

T cell co-stimulation and in vivo tolerance

Deborah J. Lenschow, Jeffrey A. Bluestone

Journal:

Current Opinion in Immunology

Année:

1993

Langue:

english

Fichier:

PDF, 679 KB

english, 1993

37

Transplantation

Jeffrey A Bluestone, Robert I Lechler

Journal:

Current Opinion in Immunology

Année:

1995

Langue:

english

Fichier:

PDF, 303 KB

english, 1995

38

Autoimmunity

Jeffrey A. Bluestone, Vijay Kuchroo

Journal:

Current Opinion in Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 99 KB

english, 2009

39

Is Antigen Specificity of Autoreactive T Cells the Key to Islet Entry?

Cristina Penaranda, Jeffrey A. Bluestone

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 606 KB

english, 2009

40

Immunotherapy of insulin-dependent diabetes mellitus

Emma L Masteller, Jeffrey A Bluestone

Journal:

Current Opinion in Immunology

Année:

2002

Langue:

english

Fichier:

PDF, 228 KB

english, 2002

41

Transplantation Transplantation tolerance — putting the pieces together

Robert Lechler, Jeffrey A Bluestone

Journal:

Current Opinion in Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 244 KB

english, 1997

42

T cell inactivation and cytokine deviation promoted by anti-CD3 mAbs

Judith A Smith, Jeffrey A Bluestone

Journal:

Current Opinion in Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 653 KB

english, 1997

43

TCRγδ cells and viruses

Roger Sciammas, Jeffrey A Bluestone

Journal:

Microbes and Infection

Année:

1999

Langue:

english

Fichier:

PDF, 121 KB

english, 1999

44

Polymorphisms and diversity of T-cell receptor-γ proteins expressed in mouse spleen

Randy Q. Cron, John E. Coligan, Jeffrey A. Bluestone

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 869 KB

english, 1990

45

Somatic cell variants ofH-2k:b: A point mutation in the first extracellular domain results in altered immune recognition

Mayumi Nakagawa, Richard A. Zeff, Steven S. Geier, Jeffrey A. Bluestone, Stanley G. Nathenson

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 536 KB

english, 1986

46

CD28/B7 regulation of autoimmune diabetes

Kevan C. Herold, Deborah J. Lenschow, Jeffrey A. Bluestone

Journal:

Immunologic Research

Année:

1997

Langue:

english

Fichier:

PDF, 1.22 MB

english, 1997

47

Therapeutic effectiveness of the immunity elicited by P815 tumor cells engineered to express the B7-2 costimulatory molecule

Ross N. La Motte, Michael A. Rubin, Eliav Barr, Jeffrey M. Leiden, Jeffrey A. Bluestone, M. B. Mokyr

Journal:

Cancer Immunology, Immunotherapy

Année:

1996

Langue:

english

Fichier:

PDF, 158 KB

english, 1996

48

T Regulatory Cells in Autoimmune Diabetes: Past Challenges, Future Prospects

Jeffrey A. Bluestone, Qizhi Tang, Caitlin E. Sedwick

Journal:

Journal of Clinical Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 227 KB

english, 2008

49

Small RNA Regulators of T Cell-Mediated Autoimmunity

Lukas T. Jeker, Jeffrey A. Bluestone

Journal:

Journal of Clinical Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 505 KB

english, 2010

50

Erratum to: Small RNA Regulators of T Cell-Mediated Autoimmunity

Lukas T. Jeker, Jeffrey A. Bluestone

Journal:

Journal of Clinical Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 45 KB

english, 2010